BiohackingDavid Sinclair protocol review: honest ingredient-by-ingredient analysis
Sinclair takes NMN, resveratrol and metformin. Which have human studies and which only work in mice? Unfiltered science-based analysis.
Biohacking
LongevitySirtuins: the 7 proteins controlling your cellular ageing
SIRT1 to SIRT7: what each does and how to activate them with NAD+, polyphenols and fasting. Sinclair explained simply. Complete evidence-based guide.
SupplementsHydroxytyrosol: the only polyphenol approved by EFSA
Only polyphenol with official claim: protects LDL from oxidation at 5mg/day. Mechanism, bioavailability and Spanish production.
SupplementsSpermidine wheat germ: natural autophagy activator explained
Spermidine from wheat germ activates autophagy at 3mg/day. Human studies show why it's 'fasting in a capsule' for longevity.
SupplementsTrans-resveratrol and pterostilbene: sirtuin activators
Pterostilbene has 80% bioavailability versus 1% for resveratrol. Why both together activate sirtuins better than alone. Complete guide with studies.
SupplementsTMG trimethylglycine: the essential methyl donor with NR
NR depletes methyls. TMG replenishes them. Without it, homocysteine rises. Dosage, mechanism and why few brands include it.
SupplementsNicotinamide Riboside (NR): the legal NAD+ precursor in the EU
NR elevates NAD+ by 51% in 8 weeks. Why it's the only precursor with solid evidence and approved in Europe. Complete science-based guide.
SupplementsNMN vs NR: Which is better (and why one is banned)
NMN banned in EU until 2027. NR is legal with stronger clinical evidence. Complete NAD+ precursor comparison backed by studies.
LongevityNAD+: The Molecule That Determines How Fast You Age
What is NAD+, why it drops 50% by age 50, and the 4 legal EU precursors to raise it. Evidence-based guide.